Research Articles
Supercharging a Microbial Workhorse: How Corynebacterium glutamicum Brews Your Lysine
Explore how metabolic engineering transforms Corynebacterium glutamicum into an efficient L-lysine production factory with advanced cellular optimization techniques.
Unlocking the Genetic Dimmer Switch: The Story of the Chicken miR-17-92 Cluster
Discover how scientists uncovered the regulatory mysteries of the chicken miR-17-92 cluster, a crucial genetic switch controlling development and disease.
The Invisible Switch: How FANCF Gene Silencing Fuels Lung Cancer
Explore how FANCF gene promoter hypermethylation disrupts DNA repair mechanisms and drives non-small cell lung cancer development through epigenetic silencing.
The Nuclear Gateway Hypothesis: How Misshapen Brain Cell Nuclei Drive Neurodegeneration
Discover how tau-induced nuclear envelope invagination causes toxic mRNA accumulation in Drosophila, revealing new insights into Alzheimer's disease mechanisms.
The Evolutionary Arms Race: How MHC Class I Genes Shaped Immune Systems from Sharks to Humans
Explore the fascinating evolution of MHC class I molecules across vertebrates and their crucial role in immune system function from sharks to humans.
The Invisible Dance: How Genes Sculpt Our Ecosystems
Explore how co-evolutionary genetics shapes ecological communities through reciprocal genetic adaptations between species.
The Invisible Engine: How Your Mitochondrial DNA Replicates to Power Life
Explore the fascinating process of mitochondrial DNA replication, its molecular machinery, and its critical role in human health and disease.
Decoding a Genetic Mystery: The Novel RUNX1 Mutation Transforming Our Understanding of Inherited Blood Disorders
Explore the discovery of a novel 3' mutation in RUNX1 gene and its implications for familial platelet disorder and leukemia predisposition.
Multiple Sequence Alignment: The Evolutionary Detective in Your DNA
How scientists decipher the hidden conversations in our genes through Multiple Sequence Alignment (MSA)
The Alzheimer's Defier: How a Protective Gene Delays Dementia by Decades
Discover how the APOE*E2 allele provides remarkable protection against Alzheimer's disease in PSEN1 E280A carriers, delaying onset by decades.