Research Articles
The Autophagy Sabotage: How a Viral Protein Fuels Liver Cancer
Discover how Hepatitis B virus HBx protein sabotages autophagy to promote liver cancer by impairing lysosomal maturation.
The Blueprint of Life: Decoding Genetic Secrets with Mammalian Interaction Maps
Exploring the revolutionary functional genomics platform for mapping genetic interactions in mammalian cells and its impact on biomedical research.
The Hidden Gatekeepers: How the CACNA2 Gene Shapes Our Nervous System
Explore how the CACNA2 gene shapes our nervous system through calcium channel regulation, impacting pain, epilepsy, and cancer therapies.
The Microscopic Warriors: How Phage JS01 Fights Drug-Resistant Staph Infections
Discover how bacteriophage JS01 offers a potential solution against antibiotic-resistant Staphylococcus aureus infections through its unique genomic features and therapeutic potential.
Decoding Parasite Secrets: How Gene Chips Are Revolutionizing the Fight Against Ancient Foes
Explore how gene chip technology is transforming parasitology research, enabling breakthroughs in understanding and combating malaria, leishmaniasis, and other parasitic diseases.
The Great Escape: How Breast Cancer Cells Outsmart Docetaxel—And How Scientists Are Fighting Back
Research on the stepwise evolution of docetaxel resistance in breast cancer cells and emerging strategies to combat it.
The Genomic Orchestra: How DNA Composition Conducts Chromatin Loops in Meiosis
Exploring how DNA's GC content regulates chromatin loop lengths during meiosis in vertebrates, with implications for genetic recombination and evolution.
The Bone-Resorption Puzzle: Why ABCA3 Isn't the Villain in Op Rats' Skeletal Defects
Discover how researchers exonerated the ABCA3 gene and uncovered the true molecular defect behind osteopetrosis in op rats, reshaping our understanding of bone metabolism.
The ABCC3 Gene: How a Molecular "Sump Pump" Drives Taxane Resistance in HER2+ Breast Cancer
Discover how ABCC3 gene amplification drives taxane resistance in HER2+ breast cancer and the latest research on overcoming this challenge.
The Invisible Armor: How a Repeating Protein Shields Cryptosporidium and Why It Matters
Discover how Cryptosporidium's unique repeating protein structure makes it resistant to environmental threats and potential therapeutic approaches targeting this molecular armor.