Research Articles
Benchmarking Functional Genomics Computational Tools: A Guide to Methods, Applications, and Best Practices
This article provides a comprehensive guide for researchers and drug development professionals on benchmarking computational tools in functional genomics.
Functional Validation of Genetic Variants: From VUS to Pathogenicity in Biomedical Research
This article provides a comprehensive guide to the functional validation of genetic variants for researchers and drug development professionals.
Evaluating Sensitivity and Specificity in Functional Assays: A Comprehensive Guide for Robust Research and Development
This article provides researchers, scientists, and drug development professionals with a comprehensive framework for evaluating the sensitivity and specificity of functional assays.
Comparative Functional Genomics Study Design: Principles, Methods, and Best Practices for Biomedical Research
This article provides a comprehensive guide to designing effective comparative functional genomics studies, tailored for researchers and drug development professionals.
EPSCs vs ESCs: A Comparative Functional Genomics Guide to Molecular Features and Therapeutic Potential
This article provides a comprehensive comparison of Expanded Potential Stem Cells (EPSCs) and Embryonic Stem Cells (ESCs) for researchers and drug development professionals.
Orthogonal Methods for Screening Hit Validation: A Strategic Guide for Robust Drug Discovery
This article provides a comprehensive guide for researchers and drug development professionals on implementing orthogonal methods to validate screening hits.
Functional Genomics Screening Strategies in 2025: A Comparative Guide for Drug Discovery and Biomedical Research
This article provides a comprehensive comparison of modern functional genomics screening strategies, tailored for researchers and drug development professionals.
A Comprehensive Guide to Benchmarking Differential Gene Expression Tools: From Foundational Principles to Clinical Applications
This comprehensive review synthesizes current methodologies and best practices for benchmarking differential gene expression (DGE) analysis tools across diverse transcriptomic data types.
Functional Validation of Genetic Variants: A Comprehensive Guide from Foundational Concepts to Clinical Protocols
This article provides researchers, scientists, and drug development professionals with a comprehensive framework for the functional validation of genetic variants.
CRISPR vs RNAi: A Comprehensive Comparison of Efficiency, Applications, and Best Practices for Genetic Research
This article provides a detailed comparison of CRISPR and RNA interference (RNAi) technologies for genetic perturbation, tailored for researchers, scientists, and drug development professionals.