Research Articles
Single-Cell RNA Sequencing in Functional Genomics: From Cellular Heterogeneity to Clinical Translation
Single-cell RNA sequencing (scRNA-seq) has revolutionized functional genomics by enabling the high-resolution dissection of gene expression at the level of individual cells.
Unlocking Gene Regulation: A Comprehensive Guide to ChIP-seq for Transcription Factor Binding Analysis
This article provides a thorough exploration of Chromatin Immunoprecipitation followed by sequencing (ChIP-seq) for mapping transcription factor (TF) binding sites genome-wide.
A Comprehensive Guide to CRISPR-Cas9 Knockout Screening: From Foundational Principles to Advanced Validation
This article provides a complete roadmap for researchers and drug development professionals to design, execute, and validate genome-scale CRISPR-Cas9 knockout screens.
The Complete RNA-seq Data Analysis Workflow: A Step-by-Step Guide from Raw Data to Biological Insight
This article provides a comprehensive guide to RNA-seq data analysis, tailored for researchers, scientists, and drug development professionals.
Model Organisms in Functional Genomics: From Gene Function to Therapeutic Discovery
This article provides a comprehensive overview of how model organisms are revolutionizing functional genomics to bridge the gap between genetic information and biological function.
From Gene to Trait: Decoding the Genotype-Phenotype Relationship for Precision Medicine and Drug Development
This article provides a comprehensive analysis of the complex relationship between genotype and phenotype, a cornerstone concept in genetics with profound implications for biomedical research and therapeutic development.
Functional Genomics Research Tools and Experimental Design: A Comprehensive Guide for Scientists
This article provides researchers, scientists, and drug development professionals with a comprehensive overview of the functional genomics landscape.
Gene Function Analysis: A Comprehensive Guide from Foundations to Clinical Applications
This article provides a comprehensive overview of modern gene function analysis, bridging fundamental concepts with cutting-edge methodologies.
Publicly Available Functional Genomics Data: A Comprehensive Guide for Researchers and Drug Developers
This article provides a comprehensive guide for researchers and drug development professionals on leveraging publicly available functional genomics data.
From Variant to Function: How Functional Genomics is Decoding Disease Mechanisms and Revolutionizing Drug Discovery
This article provides a comprehensive overview of how functional genomics is transforming our understanding of disease mechanisms and accelerating therapeutic development.