Research Articles
A Step-by-Step Guide to the ATAC-seq Protocol for Snap-Frozen Tissues: From Nuclei Isolation to Data Insights
This comprehensive guide provides researchers, scientists, and drug development professionals with a detailed, optimized protocol for performing ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing) on snap-frozen tissue samples.
A Complete Guide to ATAC-seq on Cryopreserved Cells: From Protocol Optimization to Data Validation
This comprehensive guide details an optimized ATAC-seq workflow specifically tailored for cryopreserved mammalian cells, a critical sample type in translational research.
ATAC-Seq Protocol Optimization for EPSCs: A Complete Guide to Chromatin Accessibility Profiling in Pluripotent Stem Cells
This article provides a comprehensive, step-by-step guide for performing ATAC-seq on Extended Pluripotent Stem Cells (EPSCs).
ATAC-seq Nucleosome Positioning Protocol: A Complete Guide for Researchers and Drug Discovery Scientists
This comprehensive guide details the ATAC-seq (Assay for Transposase-Accessible Chromatin with high-throughput sequencing) protocol for mapping nucleosome positions, a critical determinant of chromatin architecture and gene regulation.
ATAC-seq Nuclei Isolation: A Complete Troubleshooting Guide for Researchers
This comprehensive guide addresses the critical, yet often challenging, step of nuclei isolation for ATAC-seq.
Mitochondrial DNA Removal in ATAC-seq: Best Practices for Clean Chromatin Accessibility Data
Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq) is a powerful tool for mapping open chromatin regions genome-wide.
ATAC-Seq Library Size Selection: Methods, Optimization, and Best Practices for Chromatin Accessibility Analysis
This comprehensive guide explores ATAC-seq library size selection, a critical step for high-quality chromatin accessibility data.
A Comprehensive Guide to ATAC-seq Library Preparation with Magnetic Beads: From Fundamentals to Advanced Protocols
This guide provides a detailed, step-by-step framework for researchers and drug development professionals performing ATAC-seq library preparation using magnetic bead-based protocols.
Decoding Disease Mechanisms: A Comprehensive Guide to ATAC-seq in Disease-Relevant Cell Types
This article provides a comprehensive guide for researchers and drug development professionals on applying ATAC-seq (Assay for Transposase-Accessible Chromatin with high-throughput sequencing) to disease-relevant cell types.
ATAC-seq Guide 2024: Unveiling Transcription Factor Binding Sites for Drug Discovery
This comprehensive guide demystifies ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing) as a pivotal tool for mapping transcription factor (TF) binding and chromatin accessibility.