Research Articles
Engineering the CRISPR-CAST System in Human Cells: A Comprehensive Guide for Therapeutic Development
This article provides a detailed, current guide for researchers and drug development professionals on adapting the CRISPR-associated transposase (CAST) system for use in human cells.
The Ultimate Benchmarking Guide for Multi-Omics Integration Methods in 2024
Multi-omics integration is critical for uncovering complex biological mechanisms in biomedical research and drug discovery.
Beyond the Gel: AmpSeq vs T7E1 - A Complete Guide to Quantifying CRISPR Editing Efficiency
This article provides a comprehensive, up-to-date comparison of the T7 Endonuclease I (T7E1) assay and Amplicon Sequencing (AmpSeq) for measuring genome editing efficiency.
Unlocking Rare Cell Epigenetics: A Comprehensive Guide to Low-Input ATAC-seq
This article provides a detailed guide for researchers and drug development professionals on performing Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq) with low cell numbers.
ATAC-seq vs DNase-seq vs MNase-seq: A 2024 Guide for Epigenomic Analysis
This article provides a comprehensive comparative guide for researchers navigating the landscape of epigenomic assays for chromatin accessibility and nucleosome positioning.
Decoding Chromatin Accessibility: A Comprehensive Guide to ATAC-seq Sensitivity and Specificity for Researchers
This article provides a detailed, current analysis of ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing) performance, focusing on the critical metrics of sensitivity and specificity.
ATAC-seq Replication and Reproducibility: Essential Standards for Robust Chromatin Profiling in Research & Drug Development
This article provides a comprehensive guide to ATAC-seq replication and reproducibility standards, critical for generating reliable chromatin accessibility data.
The Definitive Guide to ATAC-seq Quality Metrics: Standards, Benchmarks, and Best Practices for Researchers
This comprehensive guide provides researchers, scientists, and drug development professionals with an in-depth analysis of ATAC-seq quality metrics and standards.
ATAC-seq QC Metrics Decoded: A Practical Guide from Raw Data to Biological Insight
This comprehensive guide demystifies ATAC-seq quality control metrics for researchers and drug development professionals.
The Complete ATAC-seq Protocol: A Step-by-Step Guide from Nuclei Isolation to Data Analysis for Researchers
This comprehensive guide provides researchers and drug development professionals with a detailed, up-to-date explanation of the Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq) protocol.