Research Articles
Functional Genomics Data Analysis Best Practices: From Raw Data to Biological Insight
This article provides a comprehensive guide to best practices in functional genomics data analysis, tailored for researchers, scientists, and drug development professionals.
Optimizing Functional Genomics Screening Libraries: Strategies for Enhanced Target Discovery in Biomedical Research
This article provides a comprehensive guide for researchers and drug development professionals on optimizing functional genomics screening libraries.
Optimizing sgRNA Design: Strategies to Maximize Efficiency and Minimize Off-Target Effects in CRISPR Applications
This article provides a comprehensive guide for researchers and drug development professionals on optimizing single-guide RNA (sgRNA) for CRISPR-Cas9 genome editing.
Multi-Omics Data Integration: A Comprehensive Guide to Methods, Applications, and Best Practices in Biomedical Research
This article provides a comprehensive overview of the rapidly evolving field of multi-omics data integration, a cornerstone of modern precision medicine and systems biology.
sgRNA Design and Efficiency Optimization: A Comprehensive Guide for Precision Genome Engineering
This article provides a comprehensive guide for researchers and drug development professionals on designing and optimizing single-guide RNAs (sgRNAs) for CRISPR applications.
Single-Cell RNA Sequencing in Functional Genomics: From Cellular Heterogeneity to Clinical Translation
Single-cell RNA sequencing (scRNA-seq) has revolutionized functional genomics by enabling the high-resolution dissection of gene expression at the level of individual cells.
Unlocking Gene Regulation: A Comprehensive Guide to ChIP-seq for Transcription Factor Binding Analysis
This article provides a thorough exploration of Chromatin Immunoprecipitation followed by sequencing (ChIP-seq) for mapping transcription factor (TF) binding sites genome-wide.
A Comprehensive Guide to CRISPR-Cas9 Knockout Screening: From Foundational Principles to Advanced Validation
This article provides a complete roadmap for researchers and drug development professionals to design, execute, and validate genome-scale CRISPR-Cas9 knockout screens.
The Complete RNA-seq Data Analysis Workflow: A Step-by-Step Guide from Raw Data to Biological Insight
This article provides a comprehensive guide to RNA-seq data analysis, tailored for researchers, scientists, and drug development professionals.
Model Organisms in Functional Genomics: From Gene Function to Therapeutic Discovery
This article provides a comprehensive overview of how model organisms are revolutionizing functional genomics to bridge the gap between genetic information and biological function.