Explore the fascinating science behind Ataxia-Telangiectasia (A-T), a rare genetic disorder that reveals our body's DNA repair mechanisms.
Discover how FKBP25, a nuclear prolyl isomerase, functions as a multifunctional suppressor of genomic instability and its role in DNA repair and cancer prevention.
Discover how the BCR-ABL oncogene promotes mutagenic DNA repair, driving cancer evolution and treatment resistance in chronic myeloid leukemia.
Discover how p53 and BLM proteins work together to repair stalled DNA replication forks and prevent cancer through homologous recombination.
Exploring the dual role of TopBP1 in DNA repair and hereditary breast cancer progression, with insights into therapeutic strategies targeting this critical protein.