Research Articles
Restoring the Guardian: How Reactivating a Single Protein Can Overcome Cancer's Drug Resistance
Discover how restoring wild-type p53 activity in p53-null HL-60 cells transforms drug-resistant cancer cells into therapy-responsive targets, offering new hope for cancer treatment.
When Cellular Gossip Turns Deadly: How Tiny Mutations Hijack Our Body's Death Machinery to Fuel Cancer
Exploring how cancer mutations hijack apoptosis through kinetic changes in protein interactions, turning cell death mechanisms into survival advantages for tumors.
The Great Cellular Hunt: Novel Tools for Tracking Cyclin-Dependent Kinase Substrates
Breakthroughs in biochemical, computational, and live-cell imaging tools revolutionizing the hunt for CDK substrates, offering new hope for smarter cancer therapies.
The Tiny Guardian: How a Fruit Fly Gene Reveals Secrets of Cancer Protection
Discover how Drosophila's p53 gene provides crucial insights into cancer protection through focused genomic responses and apoptosis mechanisms.