Discover how genome-wide association studies are revealing the genetic architecture of ischemic stroke and paving the way for personalized medicine.
Discover how rare NOX4 genetic variants drive psoriatic arthritis mutilans through excessive ROS production and oxidative stress.
Discover the groundbreaking research linking SPRY2 gene, wood smoke exposure, and asthma susceptibility through genetic-environmental interactions.
Explore how Open Targets is transforming drug discovery through systematic data integration, genetic evidence, and collaborative approaches to identify safer, more effective drug targets.
Discover how isoform-level transcriptome-wide association studies are revealing novel genetic risk mechanisms for neuropsychiatric disorders through alternative splicing analysis.
A new high-resolution dog genome is revealing thousands of previously hidden functional elements, filling gaps in our understanding of canine genetics and health.
Discover how scientists uncovered the regulatory mysteries of the chicken miR-17-92 cluster, a crucial genetic switch controlling development and disease.
Explore how co-evolutionary genetics shapes ecological communities through reciprocal genetic adaptations between species.
Explore the fascinating process of mitochondrial DNA replication, its molecular machinery, and its critical role in human health and disease.
Discover how the APOE*E2 allele provides remarkable protection against Alzheimer's disease in PSEN1 E280A carriers, delaying onset by decades.